study design
Follow-up Schedule
| Parameters | Detailed information | Screening | Baseline | 1 Y | 2 Y | 3 Y | 4 Y | 5 Y | Improvement or deterioration of clinical outcomes |
Hard outcomes (ESRD, CV outcomes) |
|---|---|---|---|---|---|---|---|---|---|---|
| Informed consent | O | |||||||||
| Demo graphic | O | |||||||||
| information | O | |||||||||
| Medical history | ||||||||||
| Medications | Hypertensive medications | O | O | O | O | O | O | O | O | |
| Immunosuppressant | O | O | O | O | O | O | O | O | ||
| Questionn aires | Health questionnaires (including smoking) | O | O | O | O | O | O | O | O | |
| KDQOL-SF version 1.3 questionnaires | O | O | O | O | O | O | O | O | ||
| Semi-food frequency questionnaires | O | O | O | O | O | O | O | O | ||
| PedsQL 4.0 Generic Core Scales (Children) | O | O | ||||||||
| Blood laboratory findings | CBC (white blood cell count, platelet, haemoglobin) | O | O | O | O | O | O | O | O | |
| Chemistry (calcium, phosphorus, glucose, blood urea nitrogen, uric acid, total protein, albumin, total bilirubin, alkaline phosphatase, AST, ALT) | O | O | O | O | O | O | O | O | ||
| IDMS-traceable Cr, eGFR | O | O | O | O | O | O | O | O | ||
| Lipid panel (total cholesterol, triglyceride, high-density lipoprotein, low density lipoprotein) | O | O | O | O | O | O | O | O | ||
| Electrolyte panel (sodium, potassium, chloride) | O | O | O | O | O | O | O | O | ||
| Total CO2 | O | O | O | O | O | O | O | O | ||
| C-reactive protein | O | O | O | O | O | O | O | O | ||
| Serology (HBsAg, HBsAb, Anti-HCV, HIV, VDRL) | O | |||||||||
| Anti-dsDNA, FANA, FANA titre, ANCA, PR3, MPO | O | |||||||||
| Complement 3, 4 | O | |||||||||
| ASO, rheumatoid factor, Cryoglobulin | O | |||||||||
| Urine laboratory findings | Random urine protein | O | O | O | O | O | O | O | O | |
| Random urine microalbumin | O | O | O | O | O | O | O | O | ||
| Random urine creatinine | O | O | O | O | O | O | O | O | ||
| Urinalysis protein | O | O | O | O | O | O | O | O | ||
| Urinalysis RBC | O | O | O | O | O | O | O | O | ||
| Kidney biopsy | Biopsy results and images including LM, IF and EM | O | ||||||||
| Report of diagnosis | O | |||||||||
| Total number of glomeruli | O | |||||||||
| Total number of global sclerosis/segmental sclerosis/crescent | O |